Asparate Aminotransferase Test (AST)

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What is an AST test?

AST (aspartate aminotransferase) is an enzyme that is found mostly in the liver, but also in muscles. When your liver is damaged, it releases AST into your bloodstream. An AST blood test measures the amount of AST in your blood. The test can help your health care provider diagnose liver damage or disease.

Other names: SGOT test, serum glutamic oxaloacetic transaminase test; aspartate transaminase test

What is it used for?

An AST blood test is often included in a routine blood screening. The test may also be used to help diagnose or monitor liver problems.

Why do I need an AST blood test?

You may get an AST blood test as part of your routine checkup or if you have symptoms of liver damage. These may include:

  • Nausea and vomiting
  • Weight loss
  • Tiredness
  • Weakness
  • Jaundice, a condition that causes your skin and eyes to turn yellow
  • Swelling and/or pain in your abdomen
  • Swelling in your ankles and legs
  • Dark-colored urine and/or light-colored stool
  • Frequent itching

Even if you don't have symptoms, your health care provider may order an AST blood test if you are at a higher risk of liver disease. Risk factors for liver disease include:

  • A family history of liver disease
  • Heavy drinking
  • Obesity
  • Diabetes
  • Taking certain medicines that can cause liver damage

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